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A few plasmids (pGL1124, pGL1224 and pGL1217) have been built to enable the replacement of one allele of CYC9, is spread through the tsetse fly and will cause trypanosomiasis in humans and animals. The two the lifetime cycle and mobile cycle in the parasite are elaborate. Trypanosomes have eleven cdc2-related kinases (CRKs) and 10 cyclins, an unusu